
The etherification of cellulose disrupts the hydrogen bonding and the resulting compounds are not ionised and more water soluble. The EFSA ANS Panel (2018) concluded that modified celluloses including ethyl and methyl, hydroxypropyl celluloses, would not be absorbed intact and not fermented in the gastrointestinal tract of animals (rat) or humans; they are excreted essentially unchanged mainly via the faeces (more than 90% of the administrated doses), while only minor amounts of metabolites and derived-products are excreted via urine or expired air (as 14CO2) and there is no indication for accumulation in the body.
What is Hydroxypropyl Methylcellulose in Vitamins?


Wie gefährlich ist HPMC?
(3) Coatings industry: As a thickener, dispersant and stabilizer in the coating industry, it has good solubility in water or organic solvents. As paint remover.
HPMC, on the other hand, is Hydroxypropyl Methylcellulose. It is produced by alkali treatment of refined cotton and further etherified using epichlorohydrin and chloromethane as etherifying agents, resulting in a nonionic mixed ether of cellulose. The degree of substitution is typically between 1.2 and 2.0, and its properties vary based on the ratio of methoxy and hydroxypropoxy groups.
Hydroxypropyl methylcellulose plays a vital role in the formulation of vitamins and dietary supplements, helping to improve their stability, bioavailability and overall efficacy. As an ingredient with multiple applications, it remains a popular choice for manufacturers looking to improve product quality while meeting the preferences and dietary requirements of a broad consumer base.
