When E171 isn’t combined with other ingredients and administered in water, some studies suggest that under these artificial conditions, E171 may be processed differently in the body resulting in some biological changes in experimental animals that are poorly understood.
For research published in 2022 study in the journal Food and Chemical Toxicology, scientists examined “the genotoxicity and the intracellular reactive oxygen species induction by physiologically relevant concentrations of three different TiO2 nanomaterials in Caco-2 and HT29-MTX-E12 intestinal cells, while considering the potential influence of the digestion process in the NMs’ physiochemical characteristics.” They found a “DNA-damaging effect dependent on the nanomaterial,” along with the micronucleus assay suggesting “effects on chromosomal integrity, an indicator of cancer risk, in the HT29-MTX-E12 cells, for all the tested TiO2 nanomaterials.” Researchers concluded that the results showcase “evidence of concern” regarding titanium dioxide used as a food additive.
The FDA's Code of Federal Regulations allows for the legal, regulated use of titanium dioxide in food products, under some restrictions.

It is a national high-tech enterprise, a national top 500 chemical enterprise, and the largest titanium dioxide exporter in China. The main products are TiO2, zirconium products, sulfuric acid and sulfate. Among them, titanium dioxide has reached 120,000 tons, and its export volume has ranked first in the country for three consecutive years. The annual production capacity of the main titanium dioxide is 600,000 tons, ranking first in Asia and fourth in the world.






titanium dioxide used for white pigments. The pigment helps to create a bright white surface that enhances the visual appeal of printed materials, making them more attractive and professional-looking. TiO2 is also used in the production of inkjet papers and photo printing papers to achieve high-quality images with sharp colors and fine details.
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Lithopone is a specialized white pigment that has been widely used in various applications, including paints, coatings, plastics, and paper industries. Known for its excellent whiteness and opacity, lithopone is predominantly composed of barium sulfate and zinc sulfide, making it an effective alternative to titanium dioxide for certain applications. As industries continue to evolve, understanding the wholesale lithopone pigment pricelist becomes essential for manufacturers and suppliers alike.
Titanium dioxide (TiO2) is renowned for its brightness, high refractive index, and stability. It comes in two primary crystalline forms rutile and anatase. Rutile is predominantly used in the production of tires due to its superior characteristics, including high UV resistance, durability, and excellent pigmentary properties. These features make TiO2 an ideal choice for enhancing the performance and longevity of tire products.
Titanium dioxide has similar uses in non-food products. It is used in sunscreen as effective protection against UVA/UVB rays from the sun, which creates a physical barrier between the sun’s rays and the skin. It’s also used to whiten paint, paper, plastic, ink, rubber, and cosmetics.



One of the primary uses of titanium dioxide is in the production of pigments for paints, coatings, and plastics. Titanium dioxide is known for its excellent opacity, brightness, and whiteness, making it an ideal choice for creating vibrant and long-lasting colors. Manufacturers of titanium dioxide carefully control the particle size and crystal structure of the pigment to ensure consistent quality and performance.

china tio2 used for paints and inks. Additionally, China has invested heavily in developing and modernizing its TiO2 production facilities, allowing the country to consistently produce high-quality TiO2 at competitive prices.