PRINCIPALES UTILISATIONS
In a 2020 study published in the Journal of Trace Elements in Medicine and Biology, researchers conducted an in vitro experiment to analyze the effects of TiO2 nanoparticles on a human neuroblastoma (SH-SY5Y) cell line. The scientists evaluated “reactive oxygen species (ROS) generation, apoptosis, cellular antioxidant response, endoplasmic reticulum stress and autophagy.” The results showed that exposure to the nanoparticles “induced ROS generation in a dose dependent manner, with values reaching up to 10 fold those of controls. Nrf2 nuclear localization and autophagy also increased in a dose dependent manner. Apoptosis increased by 4- to 10-fold compared to the control group, depending on the dose employed.”
Is titanium dioxide dangerous? Has it been linked to any health issues?
Titanium Dioxide DongFang R5566 Tio2 Powder

Public health groups urge FDA to cancel titanium dioxide in food, by Center for Science in the Public Interest, May 30, 2023

Food quality


Prices increased somewhat in the Asian market during the third quarter of 2021. After a steady recovery since mid-June, its price in India fell slightly in August, pushed down by lower import prices. Titanium dioxide prices continued to rise in the Chinese domestic market, with FOB Wuhu talks for Rutile grade TiO2 settling at 3125 USD/MT for the week ending September 24th.
Finally, it's important to consider the global trends impacting the pigment industry as a whole. Environmental regulations, technological advancements, and sustainable practices are increasingly becoming part of the conversation. Suppliers that prioritize eco-friendly production methods or offer biodegradable alternatives may appeal to buyers willing to pay a higher price for sustainably sourced materials.
