- One of the most significant applications of titanium dioxide is in the field of cosmetics. It is widely used as a sunscreen agent due to its ability to absorb ultraviolet radiation and protect the skin from harmful sun rays. Additionally, it is also used as a pigment in makeup products such as foundations, eye shadows, and blushes because of its excellent coverage and blending capabilities.
1. Pigment and Food Coloring
- When it comes to suppliers, China stands out as the major global producer and exporter of lithopone, accounting for a substantial portion of the world's supply. Chinese suppliers, known for their competitive pricing and large-scale production, have a significant influence on the global market. Companies such as Zhejiang Yinfeng Chemical Co., Ltd., Zhejiang Huayi Chemical Co., Ltd., and Shaanxi Jintai Group Co, and Shaanxi Jintai Group Co
, and Shaanxi Jintai Group Co, and Shaanxi Jintai Group Co
lithopone prices suppliers., Ltd. are some of the key players in the industry.
Free Sample TiO2 DongFang R5566 Titanium Dioxide
Titanium dioxide is one of the most widely used white pigments, often used to add whiteness and brightness to products. It is used in the production of paints, coatings, plastics and other products to provide a white color or opacity.
Funding sources
But in 2021, EFSA reevaluated titanium dioxide to consider the impacts of its nanoparticle. After considering more studies, EFSA concluded that nanoparticle-size titanium dioxide can accumulate in the body, break DNA strands and cause chromosomal damage.
Respiratory Exposure

Titanium dioxide, or TiO2, will be listed on product labels, but companies are not required to list ingredient size or structure. When it is used in sunscreens to block UV light, titanium dioxide is considered an active ingredient, which means the concentration must also be listed.
Nanotoxicology “focuses on determining the adverse effects of nanomaterials on human health and the environment.”
All samples (n = 6) were irradiated in a 96 well plate using an LED panel on top for 3 and 6 h before analysis. An identical set of samples were kept in the dark as controls. The temperature was checked and did not go over 37 °C. The intensity of light was also measured and was constant at 19,500.10 lux. (43.33 W in 0.2 m2), about 5 times less than actual solar light intensity on Earth's surface Therefore, these findings are indicative of even greater danger in real life.
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EINECS: 215-715-5
The most significant uncertainty identified by the EU experts was the concern that TiO2 particles may have genotoxic effects. Genotoxicity refers to the ability of a chemical to directly damage genetic material within a cell (DNA), which may lead to cancer in certain situations. Although the experts did not conclude that TiO2 particles in E171 are genotoxic, they could not rule out the concern that they might be.
At the present JECFA meeting, the committee considered additional toxicological studies relevant to the safety assessment of the chemical that investigated its toxicokinetics, acute toxicity, short-term toxicity, long-term toxicity and carcinogenicity, genotoxicity, and reproductive and developmental toxicity, as well as special studies addressing its short-term initiation/promotion potential for colon cancer. The experts acknowledged that a large number of toxicological studies have been conducted using test materials, including nanoparticles, having size distributions and physico-chemical properties not comparable to real-world uses of titanium dioxide as a food additive. The studies on non-representative materials were evaluated by JECFA, but the committee concluded that such studies are not relevant to the safety assessment of the additive.
A 2012 study published in the journal Environmental Science & Technology noted that children are especially exposed to titanium dioxide because of the food that contains the food additive and is particularly marketed to children, including candy and cakes.
In 2023, California and New York proposed banning several food additives that are banned in Europe but legal in the United States. Titanium dioxide was among the five proposed to be banned, but in September, the additive was removed from the list of additives from the California ban list.