In 2022, a year after the EFSA recommended against the use of E171, the Food Standards Australia New Zealand (FSANZ) conducted its own reassessment of titanium dioxide as a food additive. The agency concluded that titanium dioxide was indeed safe to use as a food additive. The United Kingdom and Canada came to similar conclusions.

In conclusion, wholesale lithopone MSDS quotes play a crucial role in ensuring the safe and responsible use of this important industrial pigment. By considering key factors such as product information, hazard identification, safety measures, emergency procedures, and regulatory compliance, businesses can make informed decisions when sourcing lithopone for their manufacturing processes. Ultimately, prioritizing safety and regulatory compliance is essential for a successful and sustainable industrial supply chain.

Lithopone 30% is the perfect solution for partial substitution of TiO2 in fillers due to its very soft nature and hardly any shrinkage properties. 

The toxicity of P25TiO₂NPs was evaluated in both prokaryotic (Fig. 3) and eukaryotic cells (Fig. 4). The XTT assay was chosen to measure the cell viability in bacterial cultures of MSSA, a normal skin microbiota microorganism. The reduction in the viability of samples with bare NPs is notorious, possibly due to the described ROS production from the interaction of P25TiO₂NPs with light [37]. This effect seems to be avoided when they are functionalized with vitamin B2. Also, the most concentrated vitaminB2@P25TiO₂NPs sample (0.2 mg/mL) shows up to 60% more absorbance after 6 h compared to the bare NPs (due to normal cell replication). This may indicate that the antioxidant effect of the vitamin B2 coating is greater than the oxidation damage produced by the NPs. This protective capacity could be attributed to the glutathione redox cycle and the conversion of reduced riboflavin to its oxidized form [38]. Values of cell viability greater than 100% are not rare and could be understood because the XTT assay actually measure metabolic activity when reducing the tetrazole to formazan. It is usually assumed that conversion is dependent on the number of viable cells, but it could also be related to an expected increased enzymatic activity when cells are exposed to small doses of some new substance. Further analysis showed that this effect was not the only one responsible for better cell viability of vitaminB@P25TiO₂NPs treated samples.

There are many ways we’re exposed to titanium dioxide in our everyday life. Below are the most common ways we encounter titanium dioxide. 

At present, the equipment and manufacturing process of domestic manufacturers of polyvinyl butyral are constantly getting closer to those abroad. For example, the wonderful use of polyvinyl butyral (PVB) has occurred in the printing industry and ceramic industry. Therefore, the domestic application of polyvinyl butyral (PVB) has an obvious upward trend in recent years.

For example, in the glass industry, it is because polyvinyl butyral (PVB) has good low-temperature impact strength, windability, light transmittance, light resistance, weather resistance, sound insulation, UV insulation and other properties, so that once the laminated glass is sealed together, the glass sandwich (i.e. laminated material) will appear as a whole and look like ordinary glass. For example, in the porcelain industry, polyvinyl butyral is made into a film and used for printing paper film of ceramic (or enamel) products. First, it reduces the original glue small paper Decal process, reduces the production cycle and production cost, and second, it makes its ceramic (or enamel) patterns bright in color and smooth in texture.

With the rapid development of science and technology in recent years, more and more industries have found the characteristics of polyvinyl butyral (PVB): high strength, high toughness, fatigue resistance, corrosion resistance and so on. Compared with traditional materials, polyvinyl butyral (PVB) is more and more widely used because of its larger development space and wider application fields!

Application field of polyvinyl butyral -- safety glass

The membrane made of polyvinyl butyral (PVB) is a special product used to manufacture safety glass and bulletproof glass. Safety glass is a special glass made of a layer of PVB diaphragm sandwiched between two layers of ordinary glass. It has good low-temperature impact strength, windability, light transmittance, light resistance, weather resistance, sound insulation, ultraviolet insulation and other properties. When subjected to strong external impact, PVB diaphragm can absorb impact energy, so that the glass will not break or prevent debris from hurting people. Moreover, the safety glass added with PVB diaphragm has the characteristics of high transparency, water resistance and aging resistance, and can be used in the environment of - 60 ℃. In addition, it can also be used as transparent material to replace plexiglass.

Application field of polyvinyl butyral -- ceramic film flower paper 

Our scientific experts applied for the first time the 2018 EFSA Scientific Committee Guidance on Nanotechnology to the safety assessment of food additives. Titanium dioxide E 171 contains at most 50% of particles in the nano range (i.e. less than 100 nanometres) to which consumers may be exposed.  

Prof. Maged Younes, Chair of EFSA’s expert Panel on Food Additives and Flavourings (FAF), wrote of the decision: “Taking into account all available scientific studies and data, the Panel concluded that titanium dioxide can no longer be considered safe as a food additive. A critical element in reaching this conclusion is that we could not exclude genotoxicity concerns after consumption of titanium dioxide particles. After oral ingestion, the absorption of titanium dioxide particles is low, however they can accumulate in the body.”