It is expected that the implementation of rutile titanium dioxide market manufacturers will be stable this week, the new single quotation of the production link will be firm, the supply of low-cost goods will be reduced, and the reference range of the overall market transaction will rise slightly. It is expected that the market transaction reference is 15200-16200 yuan/ton, and the weekly average price may refer to 15600 yuan/ton. In addition, considering the difference of orders received by different manufacturers, some manufacturers may still have 300-500 yuan/ton of negotiation room. On the demand side, most buyers still have inventory to use, so the current new batch transaction intention is not strong; On the supply side, some producers are expected to increase the load next week, so the industry time output may be slightly increased. On the whole, it is expected that the overall trading range will rise slightly next week, but most producers will adjust the real single negotiation range according to their own orders, and the new single stable price of mainstream producers.

The natural barite containing more than 95% of barium sulfate is mixed with anthracite in a ratio of 3:1 (mass), and is pulverized to a diameter of about 2 cm or less to enter a reduction furnace, and the front stage of the furnace temperature is controlled by 1000 to 1200 ° C, and the latter stage is 500 to 600 ° C, the reduction furnace rotates at a speed of 80s per revolution, the reaction conversion rate is 80% to 90%, the obtained barium sulfide enters the leaching device, the control temperature is above 65 ° C, and the content of barium sulfide is 701%, and then enters the clarification. The barrel is clarified and then added with zinc sulfate to control the zinc sulfate content to be greater than 28%, and the pH is 8-9, and a mixture of barium sulfate and zinc sulfide having a density of

In an early study Jani et al. administred rutile TiO₂ (500 nm) as a 0.1 ml of 2.5 % w/v suspension (12.5 mg/kg BW) to female Sprague Dawley rats, by oral gavage daily for 10 days and detected presence of particles in all the major gut associated lymphoid tissue as well as in distant organs such as the liver, spleen, lung and peritoneal tissue, but not in heart and kidney. The distribution and toxicity of nano- (25 nm, 80 nm) and submicron-sized (155 nm) TiO₂ particles were evaluated in mice administered a large, single, oral dosing (5 g/kg BW) by gavage. In the animals that were sacrificed two weeks later, ICP-MS analysis showed that the particles were retained mainly in liver, spleen, kidney, and lung tissues, indicating that they can be transported to other tissues and organs after uptake by the gastrointestinal tract. Interestingly, although an extremely high dose was administrated, no acute toxicity was observed. In groups exposed to 80 nm and 155 nm particles, histopathological changes were observed in the liver, kidney and in the brain. The biochemical serum parameters also indicated liver, kidney and cardiovascular damage and were higher in mice treated with nano-sized (25 or 80 nm) TiO₂ compared to submicron-sized (155 nm) TiO₂. However, the main weaknesses of this study are the use of extremely high single dose and insufficient characterisation of the particles.